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GLP-1

Tirzepatide: two receptors

What acting on GLP-1 and GIP means, and why the product matters.

PepWay Editorial Team
1 min read
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Illustrative image of research and organizing information. It does not depict a treatment outcome.
Illustrative image. It does not show a treatment outcome.

What acting on GLP-1 and GIP means, and why the product matters.

How the molecule acts

Tirzepatide activates receptors for the hormones GIP and GLP-1. EMA describes effects on insulin release in response to food and appetite regulation. The mechanism is one part of the assessment; benefits and risks are examined in studies of defined products and populations.

Authorization has a jurisdiction

In the European Union, Mounjaro has indications for type 2 diabetes and weight management in specific groups. Rules can differ between countries and formulations. Check the local leaflet for the prescribed medicine; the substance name alone does not describe all its conditions of use.

Follow-up is part of treatment

Nausea and other digestive effects appear in official information. Low blood glucose risk needs assessment, especially with insulin or sulphonylureas. Bring your medication list and agree on which symptoms to report. Do not use online comparisons to replace or adjust a treatment.

Sources and references

Documents and research consulted for this article. Each source describes its own context; a reference does not confirm every use of a substance.

  1. Mounjaro — Medicine overview (opens in a new tab)EMA · Accessed November 4, 2026
  2. Mounjaro — Product information (PDF) (opens in a new tab)EMA · Accessed November 4, 2026
  3. Alerta sobre pancreatite e uso indevido de agonistas GLP-1 (opens in a new tab)Anvisa · Accessed November 4, 2026
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